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In patients with a previous history of hypersensitivity to tinidazole or other nitroimidazole derivativesReported reactions have ranged in severity from urticaria to Stevens-Johnson syndromesee ADVERSE REACTIONSDuring first trimester of pregnancysee Use in Specific PopulationsIn nursing mothersInterruption of breast-feeding is recommended during tinidazole therapy and for 3 days following the last dosesee Use In Specific Populations

Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficult breathingswelling of your facelipstongueor throat.

Tell your doctor and pharmacist if you are allergic to tinidazolemetronidazoleFlagylor any other medicationstell your doctor and pharmacist what prescription and nonprescription medicationsvitaminsnutritional supplementsand herbal products you are takingBe sure to mention any of the followinganticoagulantsblood thinnerssuch as warfarinCoumadinantifungals such as fluconazoleDiflucanitraconazoleSporanoxand ketoconazoleNizoralcarbamazepineTegretolcimetidineTagametclarithromycinBiaxincyclosporineNeoralSandimmunedanazolDanocrinedelavirdineRescriptordexamethasoneDecadrondiltiazemCardizemDilacorTiazacerythromycinE.E.SE-MycinErythrocinethosuximideZarontinfluorouracilAdrucilfluoxetineProzacSarafemfluvoxamineLuvoxfosphenytoinCerebyxHIV protease inhibitors such as indinavirCrixivanand ritonavirNorvirisoniazidINHNydrazidlithiumLithobidmetronidazoleFlagylnefazodoneSerzoneoral contraceptivesbirth control pillsoxytetracyclineTerramycinphenobarbitalLuminalSolfotonphenytoinDilantinrifabutinMycobutinrifampinRifadinRimactanetacrolimusPrograftroglitazoneRezulintroleandomycinTAOverapamilCalanCoveraIsoptinVerelanand zafirlukastAccolateAlso tell your doctor if you are taking disulfiramAntabuseor have stopped taking it within the past 2 weeksYour doctor may need to change the doses of your medications or monitor you carefully for side effectsif you are taking cholestyramineQuestranyou should not take it at the same time that you take tinidazoleAsk your doctor or pharmacist how to space doses of these medicationstell your doctor if you have a yeast infection nowif you are being treated with dialysismechanical removal of waste in patients with kidney failureor if you have or have ever had seizures or nervous systembloodor liver diseasetell your doctor if you are pregnant or plan to become pregnantIf you become pregnant while taking tinidazolecall your doctorDo not breastfeed while you are taking tinidazole and for 3 days after you finish your treatmentknow that you should not drink alcohol while you are taking this medication and for 3 days afterwardsAlcohol may cause an upset stomachvomitingstomach crampsheadachessweatingand flushingredness of the face

Take the missed dose as soon as you remember itHoweverif it is almost time for the next doseskip the missed dose and continue your regular dosing scheduleDo not take a double dose to make up for a missed one.

Another medication that is similar to tinidazole has caused cancer in laboratory animalsIt is not known whether tinidazole increases the risk of developing cancer in laboratory animals or in humans.Talk to your doctor about the risks and benefits of using this medication.

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in patients with all four amsel s criteria and with a baseline nugent score 4, tinidazole oral tablets given as either 2 g once daily for 2 days or 1 g once daily for 5 days demonstrated superior efficacy over placebo tablets as measured by therapeutic cure, clinical cure, and a microbiologic cure.